Explore this annual collection of free articles that NEJM editors selected as the most meaningful in changing clinical practice and improving patient care in 2025. | The New England Journal of Medicine

Editor-in-Chief Jeffrey M. Drazen, M.D., highlights three of the Notable Articles of 2016 published in the New England Journal of Medicine: incidence of dementia in the Framingham Heart Study, a randomized trial of labor induction in women over 35, and a 10-year outcomes study in men with prostate cancer. Access the collection at nejm.org/nejm-special. | The New England Journal of Medicine

A 21-month-old boy presented with a 1-day history of a pruritic rash on his left leg. On examination of the left lower leg, an edematous erythematous plaque was pulsating with alternating erythema and blanching in synchrony with his pulse. What is the most likely diagnosis? To submit your diagnosis, click the link: https://nej.md/2Ku5WxD | The New England Journal of Medicine

132K views · 420 reactions | Keeping up with medical breakthroughs, clinical best practices, and relevant research is now easier. Rediscover NEJM.org. www.nejm.org/revitalized | The New England Journal of Medicine | Facebook

21K views · 104 reactions | NEJM Editorial Fellow Abarna Pearl, MD, MPH, summarizes the ALPACA trial. Read the full trial results: https://nej.md/4kWjJyn | The New England Journal of Medicine | Facebook

81K views · 1.9K reactions | For patients with hemophilia, the goal...