For decades, lab-grown cells have been studied in materials that don't reflect the softness and flexibility of human tissue.

Distinct human populations living on separate continents have followed largely similar patterns of evolution since the onset of the Neolithic period, according to a new study. This suggests that, ...

Dried blood spot sampling offers a scalable strategy to close diagnostic gaps and improve global surveillance for cardiovascular‐kidney‐metabolic syndrome. However, assay performance and the extent of ...

Much of our public debate today rests on a simple but mistaken premise: that a well-functioning society is made up of largely self-sufficient individuals, and that public systems should reward ...

A new human liver organoid microarray developed by Cincinnati Children’s and Roche recreates immune-driven liver injury in the lab. Built from patient-derived stem cells and immune cells, it ...

Example of human liver organoids co-cultured with autologous CD8 T cells (green). These tissues can be used during drug development to predict liver toxicity, according to new resaerch published by ...

Researchers from the Hong Kong University of Science and Technology, MiniMax, and University of Waterloo have released a new framework for creating smarter and more efficient web search and browsing ...

Clinicians' ability to diagnose and treat chronic diseases is limited by scientific uncertainty around factors contributing to disease risk. A study published September 2 nd in the open-access journal ...

Structural variants (SVs) are alterations in the DNA sequence that involve large-scale changes, typically longer than 50 base pairs. Advances in long-read sequencing have significantly increased ...

Completed in 2003, the Human Genome Project gave us the first sequence of the human genome, albeit based on DNA from a small handful of people. Building upon its success, the 1000 Genomes Project was ...

Researchers have significantly expanded the catalogue of known human genetic variation. The resulting datasets, shared in two back-to-back publications in the journal Nature, constitute what may be ...