Grand Pharmaceutical Group Limited announced that its experimental drug STC3141 met the primary clinical endpoint in a Phase II trial conducted across sites in China, delivering a statistically ...

Researchers use a machine learning approach to improve the stability and performance of antibodies inside cells.

Prostate cancer is one of the most prevalent malignancies globally. This cancerous condition originates within the prostate gland, an integral part of the male reproductive system. The molecular ...

ABSTRACT: Forensic epigenetics has become a rapidly expanding frontier in molecular forensics, offering analytical capabilities that surpass those of traditional genetic markers. Advances in ...

ABSTRACT: Epigenetic mechanisms regulate and stabilize a broad range of biological processes without altering the primary DNA sequence. This regulation is achieved through DNA methylation, ...

Introduction: Excess lipolysis and dysregulated fatty acid oxidation can exacerbate neuroglial injury and impair neurodevelopment. Neurodevelopment is also regulated by histone deacetylation and ...

Salt stress remains a critical challenge for plant growth, especially in crops like pea (Pisum sativum L.). This study explores the role of histone modifications in regulating pea's response to salt ...

A picture of a mouse MII stage eggs with the location of chromosomes (green) and the distribution of the histone modification H3K4me3 (purple). The team confirmed that H3K4me3 was significantly ...

The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the next generation. Now, researchers from Kyushu University have demonstrated ...

Epigenetic modifications, particularly histone post-translational modifications (PTMs), are central to pediatric brain tumor pathogenesis, impacting chromatin structure, gene expression, and genomic ...

Nucleosomes--which are composed of histone proteins (purple) wrapped in strands of DNA (green)--appear to regulate gene activity via inherent biophysical properties. For decades, scientists have known ...