A new study has uncovered a hidden step that helps the deadliest malaria parasite survive and multiply inside the human body. Researchers studying Plasmodium falciparum found that the parasite relies ...
Kazia Therapeutics , an oncology-focused pharmaceutical company developing novel therapies for difficult-to-treat cancers, ...
Cell division is a fundamental process that allows cells to replicate accurately and maintain tissue homeostasis. This ...
The authors present convincing data to validate abscisic acid-induced dimerisation to induce a synthetic spindle assembly checkpoint (SAC) arrest that will be of particular importance to analyse ...
This study identifies the uncharacterised protein FAM53C as a novel, potential regulator of the G1/S cell cycle transition, linking its function to the DYRK1A kinase and the RB/p53 pathways. The work ...
Please provide your email address to receive an email when new articles are posted on . A one-time infusion of BMS-986353, a CD19 CAR T-cell therapy, improved lung function and skin thickness.
Background: The adult mammalian heart exhibits limited regenerative capability, primarily due to the postnatal arrest of the cardiomyocyte (CM) cell cycle. Aim: To elucidate the role of checkpoint ...
CULVER CITY, Calif.--(BUSINESS WIRE)--ImmunityBio, Inc. (NASDAQ: IBRX), a leading immunotherapy company, today announced new paradigm changing findings from the Phase 2 QUILT-3.055 study, ...
New research from Dana-Farber Cancer Institute shows that a new class of drug results in cell death in cancers, such as small cell lung cancer, with a disabled quality control cell cycle checkpoint ...
Schrödinger has halted development of its cancer-fighting candidate SGR-2921 after two patients treated with the cell division cycle 7 (CDC7) inhibitor died in a Phase I trial. The trial (NCT05961839) ...
A new comprehensive review reveals that harnessing natural killer (NK) cells by blocking their “off-switches” could significantly enhance cancer immunotherapy, providing new avenues for treating solid ...
Use of Ablative Radiotherapy in the Setting of Oligometastatic Disease A retrospective analysis of 3,626 patients treated with ICIs for various malignancies within a single health system was conducted ...
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