The development of new therapeutics targeting protein kinases is crucial in the fight against diseases like cancer.

Metabolites can inhibit the enzymes that generate them. To explore the general nature of metabolic self-inhibition, we surveyed enzymological data accrued from a century of experimentation and ...

Reply letter to Dr. Wojtasek regarding: Oxidation of flavonoids by tyrosinase and by o-quinones-comment on "Flavonoids as tyrosinase inhibitors in in silico and in vitro models: basic framework of SAR ...

A near-universal way to measure enzyme inhibition. ScienceDaily. Retrieved December 20, 2025 from www.sciencedaily.com / releases / 2018 / 03 / 180301103613.htm McGill University. "A near-universal ...

The study was conducted by researchers from Scripps Research; the Genomics Research Center, Academia Sinica, Taiwan; and the National Taiwan University. It is being published today in the journal ...

Using computational tools and virtual screening, researchers at the Center for Redox Processes in Biomedicine (Redoxoma) have ...

Research has shown that angiotensin converting enzyme (ACE) inhibitors help manage diabetic nephropathy-related issues. They can also slow the progression of diabetic nephropathy in some people.

Recent evidence suggests that natural products are much more than simply agents of “microbial warfare” and actually play critical roles in bacterial pathogenesis and communication. In particular, ...

Background: Perchlorate (ClO₄⁻) is an environmental contaminant known to disrupt the thyroid axis of many terrestrial and aquatic species. ClO₄⁻ competitively inhibits iodide uptake into the thyroid ...

Amiprophos-methyl (APM), a phosphoric amide herbicide, was previously reported to inhibit the in vitro polymerization of isolated plant tubulin (L.C. Morejohn, D.E. Fosket [1984] Science 224: 874-876) ...

In the context of the coronavirus disease 2019 (COVID-19) pandemic, with over 3.5 million deaths and counting as of June 9, 2021, the development of effective antivirals remains essential. This ...