Using more exacting analytical tools can give a clearer assessment of gene-editing outcomes. Although many have never heard of it, β-thalassemia is one of the most common autosomal recessive diseases ...

Circulating miRNA Signature Predicts Response to Preoperative Chemoradiotherapy in Locally Advanced Rectal Cancer We developed a ddPCR assay to sensitively detect tumor-derived hypermethylated RASSF1A ...

Clinical Utility of Real-Time Targeted Molecular Profiling in the Clinical Management of Ovarian Cancer: The ALLOCATE Study Plasma cfDNA and pathology specimens of 36 patients were analyzed. Agreement ...

A recently published paper in the Journal of Virological Methods is the first to directly compare ddPCR technology to RT-qPCR with multiplexed assays using the same reaction mix and cycling protocol ...

ddPCR is a highly sensitive tool designed to detect and quantify rare genetic variants, and it can be used to detect outcomes of CRISPR editing. For example, ddPCR assays can detect CRISPR edits via ...