X-linked severe combined immunodeficiency disease (X-SCID) is a rare genetic disorder characterized by profound defects in T-cell, B-cell, and natural killer (NK) cell function, caused by mutations in ...
(L to R) First author Anoop Babu Vasandan, PhD, St. Jude Department of Immunology, co-corresponding author Caitlin Zebley, MD, PhD, St. Department of Bone Marrow Transplantation & Cellular Therapy and ...
Findings from St. Jude Children's Research Hospital demonstrate that virtual memory T cells, a specialized group of immune cells, provide nonspecific immunity for infants early in life. Patients with ...
The US Food and Drug Administration (FDA) halted 27 gene therapy trials Tuesday following indications that a second child is showing signs of leukemia after treatment for X-linked Severe Combined ...
Current GT strategies employ viral vectors (eg, murine g-retroviruses or lentiviruses) to introduce genetic material into isolated HSCs. However, gene editing (eg, CRISPR-based GT) is under active ...
Skin cancer is typically caused by damage to the skin's cells from ultraviolet radiation. But a recent case study has just shed light on another potential cause: human papillomavirus. Early results ...
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