A recent review article highlights evolving MS-based methodologies that are reshaping ligand discovery and mechanistic characterization for membrane protein drug targets. LCGC International spoke to ...

Transmembrane proteins are essential for the survival and function of all living cells. They are involved in virtually every biological process, making them a vital target for drug development.

An international team including researchers from MIPT’s Laboratory for Advanced Studies of Membrane Proteins have proposed an explanation of the way bacteria process external signals. By identifying ...

STEAP1 (Six-transmembrane epithelial antigen of the prostate 1), which was first found in prostate cancer, is a member of the STEAP protein family that is largely expressed in prostate epithelial ...

ATP-binding cassette (ABC) transporters are transmembrane proteins essential for the biliary secretion of bilirubin, bile acids, phospholipids, and ...

Located at the cellular interface, membrane proteins play critical regulatory roles in the signaling between a cell and its interacting environment, making them popular and ideal drug targets.