March 30, 2004 -- People who are at risk of iron overload because of elevated transferrin saturation levels and who ingest high levels of dietary iron have a mortality risk 2.9 times greater than ...

Recently discovered genetic mutations, modern diagnostic techniques, and fresh approaches to therapy change the outlook on hemochromatosis. Ben, age 46, visited his primary-care clinician with ...

Saturation of TfR1 leads to the dissociation of Hfe and the binding of the alter to the TfR2, which in turn influences the binding of BMP6 to its receptors on the membrane. Increased liver iron ...

For absorption studies, the orally administered test solution consisted of radioactive ferrous citrate (Fe 59), usually about 8 microcuries, and carrier ferrous sulfate mixed in the desired ratio in 0 ...

Patients with nonalcoholic fatty liver disease (NAFLD) had a significantly higher risk of developing hepatocellular carcinoma (HCC) based on elevated biomarker levels of serum iron or transferrin ...

A 34-year-old, healthy, African-American man with no chronic medical problems is found to have a high serum iron level (266 µg/dL, normal: 40-155) along with normal aspartate aminotransferase, alanine ...

Background: Recently it has been found that iron is an important element in the natural history of hepatitis C. Serum markers of iron stores are frequently increased in chronic hepatitis C virus (HCV) ...

Iron intake and soluble transferrin receptor were positively associated with insulin resistance, whereas serum iron and transferrin receptor were negatively associated. Disturbances in iron metabolism ...

Alcohol and iron are believed to have a synergistic effect in the development of liver injury. Furthermore, alcohol enhances iron absorption. Primary hemochromatosis is a genetic disorder, mostly ...