Experts agree that combination approaches, which may or may not include chemotherapy, will drive improved patient outcomes in oncology.

Targeted therapies are a type of medicine used to treat cancer. They work differently than standard chemotherapy. Instead of killing all fast-growing cells or keeping them from dividing, targeted ...

A TOPOGRAPH-based hierarchy stratifies biomarker–drug pairs from regulatory/positive trial evidence (tiers 1–3A) to repurposing across histotypes (3B), preclinical/early data (4), and suspected ...

Targeted therapies are cancer medications that work more selectively than standard chemotherapy medications. They do this by targeting specific molecules or genetic changes in cancer cells in order to ...

A two-decade review of thyroid cancer mortality among older adults in the U.S. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does not include a full text ...

Earlier deployment of ARPIs, PARP inhibitors, and PSMA radioligand therapy yields deeper initial control but creates heavily pretreated mCRPC with complex resistance and cumulative toxicity ...

Across treatment classes, CH associated with increased therapy-related cytopenias, particularly neutropenia, and DNMT3A/TET2 ...

Lung cancer in never-smokers exhibits distinct biological characteristics, often leading to late-stage diagnoses due to lack of screening. Targeted therapies, guided by molecular testing, offer ...

ORNL is a leader both in developing advanced radiotherapies and in providing the radioisotopes needed for those therapies.

Mayo Clinic researchers used milk-based nanoparticles to deliver siRNA into bile duct cancer cells. This targeted therapy ...

Targeted therapy is reaching more patients than ever, but access still depends on factors like cost, insurance coverage, geography, and cancer type. These treatments offer precision and strong ...

L1, EBV and mismatch repair deficiency suggests CLDN18.2 stratification must be integrated into multi-biomarker algorithms rather than used in isolation. Treatment interactions emerged: CLDN18.2-high ...