For years, biomolecular condensates were thought to be simple, liquid-like droplets with little internal organization. New ...

RAB7A plays a central role in the final stages of autophagy, facilitating autophagosome-lysosome fusion, lysosome positioning, and cargo degradation. Its activation by guanine nucleotide exchange ...

Orthohantaviruses, such as the Puumala virus, are widespread in Europe, causing flu-like illnesses and severe kidney damage in those infected. It is increasingly considered a zoonotic threat.

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought. The ...

Researchers have developed a human intestinal cell model that closely mimics the structure and function of the human gut, enabling more precise prediction of drug-induced gastrointestinal toxicity ...

Even after decades of peering into cells, biologists are still finding surprises. In a twist, researchers at the University of Virginia and the National Institutes of Health uncovered a new organelle, ...

Herpes simplex virus partially liquifies the tightly packed, gel-like interior of human cell nuclei to copy itself faster, a new study shows. The research centers on how the nucleus of each human cell ...