Cryo-EM structures reveal conformational dynamics behind AP-4 membrane trafficking

Adaptor protein (AP) complexes play central roles in intracellular vesicular trafficking by coupling cargo selection to ...
Medicine Buffalo

The Cryo-Electron Microscopy Center

The Cryo-Electron Microscopy Center supports industry, academic, government, and non-profit research institutes, providing single-particle and microcrystal electron diffraction capabilities. We offer ...
Technology Networks

From Sub-Cellular to Whole-Cell: Biological Imaging With Cryo-EM

Discover how new developments in cryo-electron microscopy are set to transform biological imaging by supporting more targeted ...
Medicine Buffalo

Research Services: Accelerating Discovery

UB-HWI offers a range of Structural Services to academic and industrial partners including single-particle cryo-EM, microcrystal-electron diffraction, and crystallization screening. Our philosophy is ...
Labroots

Next-Gen Cryo-EM: Advancing Cellular and Structural Biology

Cryo-electron microscopy (cryo-EM) has revolutionalized our understanding of the intricate molecular machinery that governs life. It has elucidated the three-dimensional (3D) structure of biological ...
Brandeis University

School of Science, Engineering and Technology

The Tundra Cryo TEM is equipped with an x-FEG and Falcon-C Direct Detector. It has a semi autoloader using autogrids, allowing for the retrieval of grids in case a user would like to continue imaging ...