Membrane protein targeting and insertion is a fundamental process in cellular biology that ensures proteins are correctly delivered to, and integrated within, the lipid bilayer. Proteins destined for ...

Acurastem received a grant to develop ALS therapies targeting SYF2, a regulator of TDP-43, in collaboration with academic research teams.

Researchers have created nanoparticles that can remove disease-driving proteins while also delivering a chemotherapeutic or ...

Researchers led by  Dr. Xavier Salvatella have uncovered the mechanism by which an experimental drug is able to block intrinsically disordered proteins, which were previously considered “undruggable”.

Cellular membrane proteins play important roles in cellular transport, signaling, and cell-to-cell communication. Malfunction in membrane proteins can lead to serious diseases, such as cancer. However ...

Panelists discuss how amyloid-targeting therapies for Alzheimer disease represent a breakthrough drug class that works by binding to and removing beta-amyloid plaques through various mechanisms, ...

Spread the loveIn a groundbreaking study published on March 15, 2026, researchers from Houston Methodist have unveiled a crucial protein associated with amyotrophic lateral sclerosis (ALS) and ...

An estimated 20 percent of adults in the US experience chronic pain. 1 To help patients manage their condition, clinicians have employed one main type of pain-relieving drug: opioids. With their ...

Intrinsically disordered proteins lack a fixed structure, which is why they have been considered "undruggable" targets for ...

PTIR calculates the rates at which originally monomeric proteins are transformed into aggregates at various temperatures under initial-rate settings. Utilizing SMSLS for identical conditions generates ...