The key to attacking 'undruggable' proteins: Transient clustering state reveals a moving target

Intrinsically disordered proteins lack a fixed structure, which is why they have been considered "undruggable" targets for ...

Benchmark of 1.4 million checked protein structures could sharpen AI predictions

University of Missouri researchers have released the world's largest collection of protein models with quality assessment—a ...
The Stanford Daily

First lysosomal protein atlas aims to advance neurodegenerative research

The Abu-Remaileh Lab published an atlas of proteins, found in lysosomes across different brain cell types, to advance research on neurodegenerative diseases.
Science Daily

Protein mutant stability can be inferred from AI-predicted structures

Researchers have taken a significant step forward in understanding the stability of proteins by leveraging the power of AI. The research team used AlphaFold2 to explore how mutations affect protein ...
Knowridge Science Report

A new blood test may detect Alzheimer’s earlier

Scientists have developed a new type of blood test that may improve how Alzheimer’s disease is detected and understood. Unlike most current blood tests, which measure how much of certain proteins are ...

1 protein to rule them all – why crowning the protein that makes jellyfish glow green as a model can help scientists streamline biology

Researchers have been studying tens of thousands of proteins and even more variations without a yardstick to compare their ...