This article was review by Thomas Cooper, MD from Baylor College of Medicine. Stay up to date on the latest science with Brush Up Summaries. Despite its significance, alternative splicing’s global ...

Protein splicing is a naturally occurring post‐translational process in which inteins, as self‐excising protein segments, precisely remove themselves from a host polypeptide and concomitantly ligate ...

Researchers uncovered how polyamines influence cell fate by altering protein phosphorylation and alternative splicing. The ...

Inteins are autoprocessing domains that cut themselves out of host proteins in a traceless manner. This process, known as protein splicing, involves multiple chemical steps that must be coordinated to ...

Pre-mRNA splicing in a subset of human short introns is governed by a distinct mechanism involving a new splicing factor, new research finds. The interrupted non-coding regions in pre-mRNAs, termed ...

Alternative splicing, a clever way a cell generates many different variations of messenger RNAs -- single-stranded RNAs involved in protein synthesis -- and proteins from the same stretch of DNA, ...

In a new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the DOC2A ...

Transgenic worm in which the splicing factor UNC-75, marked with the fluorophore mScarlet, reveals its expression throughout the nervous system. The worm was generated using CRISPR-Cas9 gene editing ...

What kills most people who die from cancer is not the initial tumor. It’s the intolerable disease burden on the body that arises when tumor cells continually expand their numbers after spreading to ...

Polyamines are small molecules naturally present in all cells and are critical in guiding cellular decisions, whereas an ...