A hallmark of Parkinson's disease is the buildup of Lewy bodies—misfolded clumps of the protein known as alpha-synuclein.

Cancer cells carry thousands of mutations, but not all mutations are created equal. Some make tumors highly visible to the ...

Researchers from the HUN-REN Szeged Biological Research Centre and HCEMM have just published a new study suggesting that it's ...

Researchers have elucidated key steps in the ubiquitin tagging of the mutated huntingtin protein, providing hope for future ...

A hallmark of Parkinson's disease is the buildup of Lewy bodies — misfolded clumps of the protein known as alpha-synuclein.Long before ...

A University of Massachusetts Amherst scientist has discovered that a mutation in the misfolding protein that causes Parkinson's disease offers protection against another fatal neurodegenerative ...

Researchers found that paired pathogenic variants can restore protein function rather than make it worse. This phenomenon ...

Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumor growth ...

In humans, hundreds of proteins interact in a complex network dubbed the interactome. Those interactions are further complicated when disease-causing mutations are introduced into genes that code for ...