Mount Sinai researchers have discovered that Polycomb complexes, groups of proteins that maintain gene expression patterns, are essential for proper skin development, according to a paper published in ...
Most of our genome is often written off as “junk DNA”, meaning it doesn’t encode for genes that get made into proteins. This so-called junk consists of accumulated DNA elements like viral DNA that got ...
Patterning of the floral organs is exquisitely controlled and executed by four classes of homeotic regulators. Among these, the class B and class C floral homeotic regulators are of central importance ...
A mounting body of evidence is uncovering how the polycomb group (PcG) proteins play a key role in the initiation, development, and progression of cancer in humans. Image Credit: ibreakstock / ...
Prostate cancer becomes fatal when associated with metastasis. In the October 10 Nature, Sooryanarayana Varambally and colleagues describe a microarray-based analysis of genes whose expression is ...
A multi-institutional study has discovered spontaneous mutations in RNF2 (RING2) gene as the underlying cause of a novel neurological disorder. A multi-institutional study has discovered spontaneous ...
Polycomb-repressive complexes (PRCs) play key roles in development by repressing a large number of genes involved in various functions. Much, however, remains to be discovered about PRC-silencing ...
Two Polycomb complexes have been found to act together to control the development of skin and can cover for each other if one complex is damaged. A recent study led by researchers at the Icahn School ...
The roots of cancer run deep. Indeed, they’re usually assumed to run all the way to the blighted bits of DNA we call oncogenic mutations. But what if they don’t have to run quite that deep? What if ...
A multi-institutional study has discovered spontaneous mutations in RNF2 (RING2) gene as the underlying cause of a novel neurological disorder. This Undiagnosed Diseases Network (UDN) study was led by ...
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