Platelets are small, anucleate blood cells that play an essential role in hemostasis. Their primary task is to recognize vascular injury, become activated, and aggregate via their surface receptor ...

A team from Würzburg has fundamentally changed our understanding of platelet biology. The researchers demonstrate that the surface protein integrin αIIbβ3 is not only a key molecule in blood clotting, ...

The fundamental role of platelets in haemostasis and thrombosis relies on their capability of adhesion to specific locations of the perturbed vessel wall upon injury, damage or inflammation. Continued ...

The hemostatic system is maintained by a delicate balance of pro- and anticoagulant factors, allowing for physiologic response to hemorrhage while simultaneously avoiding development of pathologic ...