ALS is the most common form of Motor Neuron Disease (MND) in adults. An early hallmark of ALS is the breakdown of neuromuscular junctions—the connection between the end of a motor nerve and a ...
The muscle transmembrane protein Vangl2 helps organize the development and maintenance of connections between muscles and motor neurons, a study concludes. A skeletal muscle isn’t much use without a ...
MIT scientists find that motor neuron growth increased significantly over 5 days in response to biochemical (left) and mechanical (right) signals related to exercise. The green ball represents cluster ...
The test was developed by researchers at the US-based not-for-profit Brain Chemistry Labs, who analysed 788 blood samples – roughly half from patients with the disease and half from people without it.
The formation and maintenance of neuromuscular junctions are activity-dependent processes. This means that, without regular stimulation, grafted motor neurons may survive but are unlikely to form ...