Membrane proteins are vital for cellular signaling, transport, and communication, making them attractive drug targets despite their challenging properties. Advances in mass spectrometry have enabled ...

Edward Lyman, associate professor in the departments of physics and astronomy, as well as chemistry and biochemistry, was recently published in the journal Nature Chemical Biology. The article, “When ...

Membrane proteins play an essential role in countless biological processes and are pivotal targets in drug discovery. However, their inherent amphipathic nature necessitates the development of ...

Cellular membrane proteins play many important roles throughout the body, including transporting substances in and out of the cell, transmitting signals, speeding up reactions and helping neighboring ...

Adaptor protein (AP) complexes play central roles in intracellular vesicular trafficking by coupling cargo selection to ...

Researchers from the Heart Center of the University Medical Center Göttingen (UMG) led by Priv.-Doz. Dr. Sören Brandenburg have identified a protein that plays a central role in the heart's adaptation ...

Precise methods for shredding or repairing and replacing specific cancer-causing proteins in a malignant cell, developed at ...

Gram-negative bacteria pose a significant threat to global health due to their high resistance to antibiotics compared to that of Gram-positive bacteria. Their formidable defensive capabilities stem ...

The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are essential for a wide range of cellular functions—as enzymes, transporters, ...

Cancer cells have softer membranes than healthy cells. New nanoparticles exploit this physical difference to fuse selectively ...