Light microscopy is a cornerstone in life sciences technology, having experienced considerable diversification since its inception. This development becomes visible when considering the distinctive ...

Light-sheet microscopy has emerged as a transformative imaging modality that enables rapid, three‐dimensional visualisation of biological specimens with minimal photodamage. By illuminating samples ...

Are you studying complex biological structures such as vasculatures or neuronal networks but feel like you're not seeing the whole picture? Step into a new dimension with the UltraMicroscope Blaze™ ...

Researchers have incorporated a swept illumination source into an open-top light-sheet microscope to enable improved optical sectioning over a larger area of view. The advance makes the technique more ...

Analyzing the response of cells to heat shock is an established way to study the behavior of cells in changing conditions, and understand their natural survival mechanisms. A project at the University ...

descSPIM enables three-dimensional imaging of diverse tissues like neural cells and cancerous tumors. The widespread dissemination and adoption of descSPIM can accelerate biomedical discoveries. Three ...

SLICE addresses one of the most significant challenges in modern biological research: the limited accessibility of high-performance light sheet microscopy due to high costs and complex infrastructure ...

Light-sheet microscopy (LSM) techniques are designed to illuminate thin slices of a larger sample with perpendicular laser illumination, as a way to improve signal-to-noise performance and reduce ...

A new protocol extends live imaging time for C. elegans larvae and adults using light sheet fluorescence microscopy from 20 minutes to more than 2 hours, while avoiding heat stress in the specimen.

Two heads are better than one, as the saying goes, and sometimes two instruments, ingeniously recombined, can accomplish feats that neither could have done on its own. The microscope combines ...

Researchers developed a large-scale, dynamic imaging technique using mesoscopic oblique plane microscopy, which can capture 3D images of entire organisms and maintain cellular resolution. A new ...