The colonic mucosal barrier is essential for maintaining digestive health, protecting against pathogens, and preventing inflammation. The Notch signaling pathway is implicated in these processes, as ...

Altered intestinal barrier function is postulated to be a central predisposing factor to intestinal diseases, including inflammatory bowel diseases and food allergies. However, the mechanisms involved ...

Radhakrishna Rao, PhD, vice-chair and professor in the Department of Physiology at the University of Tennessee Health Science Center (UTHSC), has received two large national awards totaling $5 million ...

From Ayurveda to the teachings of Hippocrates, medicine's earliest traditions advanced a belief that the gut was the foundation of all health and disease. It wasn't until recently, however, that ...

Western diets that are high in sugars, fats, and processed foods have been linked to a wide variety of health ailments. Now, researchers have determined that Western diets can also disrupt the crucial ...

Researchers at Applied Biological Laboratories Inc. discovered how natural bioactive molecules can effectively relieve cold and flu symptoms by protecting the mucosal barrier function and reducing ...

A: Animal; ACE: Accessory cholera enterotoxin; H: Human; ZOT: Zonula occludens toxin.

Background Both host and microbe metabolism of tryptophan (Trp) is altered in diabetes; however, the molecular mechanisms are ...

A research team led by the Medical University of Vienna and the University of Vienna has investigated a possible link between ...

The intestinal mucosa absorbs nutrients, water, and electrolytes in a controlled manner–while simultaneously keeping out toxins, allergens, and some bacteria. When this barrier is damaged, it is ...