Human DNA constantly refolds in 3D space, and these looping dynamics regulate gene expression and cell identity.

For decades, scientists believed a fertilized egg’s DNA began as a shapeless mass, only organizing itself once the embryo switched on its genes. But new research reveals that the genome is already ...

Scientists have identified how specific genetic changes function in cells to influence disease risk and other human health ...

DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave. Researchers have now mapped this hidden architecture in unprecedented detail, showing ...

The DNA of human cells consists of a sequence of about 3.1 billion building blocks. Cells go to great lengths to maintain the integrity of this vast store of information. They constantly untangle ...

Mitochondrial diseases are severe, often untreatable, and they leave human cells unable to grow normally without outside help. A new study published in Nature Metabolism now shows that a single gene ...