High performance liquid chromatography (HPLC) is an analytical technique used to separate, identify, quantify, and purify individual components of a mixture. This technique is very common in ...

For some chromatographers, their first inkling that high-performance liquid chromatography was going to be a big deal came in 1969. That year, they traveled to Las Vegas to attend the fifth in a ...

As analytical technology continues to advance, both regulatory agencies and pharmaceutical companies are keen to avail themselves of these enhancements. In the case of chromatography, evolution from ...

High-performance liquid chromatography (HPLC) gives chemists access to a world of knowledge about molecules both large and small. When combined with high-resolution detection methods such as mass ...

High performance liquid chromatography (HPLC) was first described in a landmark paper by Csaba Horvath and Seymour Lipsky in 1966, followed by the 1967 debut of the Waters ALC-100. Over the next ...

When conducting reproducible and interference-free analysis by liquid chromatography, the purity of the solvents used, particularly the purity of water, is crucial for the sensitivity of this method, ...

Investigation of peak purity failure during HPLC method validation led to discovery of a co-eluting impurity under the main peak. Spectral analysis, including three-dimensional modelling, was used to ...

Liquid chromatography is a technique of key importance for many areas of chemical analysis and one that has evolved with the progression of technology and instrumentation over time. Here we highlight ...

Operating HPLC at higher than ambient temperatures can improve peak shapes and enable faster run times. Preheating the mobile phase is significant in high temperature liquid chromatography as the ...

High performance liquid chromatography, more commonly known by the acronym HPLC, is a method used to identify substances in a mixture. There are several types of HPLC, such as reversed-phase, ...