Single-cell RNA sequencing of endometrial samples across the menstrual cycle identified key cell types and gene signatures ...

Missing genes and sequencing read registration in single-cell RNA-seq experiments. Credit: Nature Methods (2023). DOI: 10.1038/s41592-023-02003-w In 2018, researchers in the Caltech laboratory of Yuki ...

Learn about comparative gene expression studies in Alzheimer's disease and other conditions in Mayo Clinic's Precision Medicine in Neurodegeneration Lab.

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years. Though ...

Researchers create a massive single-cell atlas of the aging mouse brain, revealing how epigenetic changes and "jumping genes" drive neurodegeneration.

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to ...

Our brain is arguably the organ that most distinguishes humans from other primates. Its exceptional size, complexity and capabilities far exceed those of any other species on Earth. Yet humans share ...

Researchers at the Mount Sinai Center for Transformative Disease Modeling used multi-omics genetic analysis tools to identify 4,749 key gene clusters, termed “prognostic modules,” which they say ...

Research uncovering the origin of pineoblastoma, a rare pediatric brain tumor, has also revealed a dependency across multiple ...

A newly released publication examines how deuterium concentration may influence gene activity in lung cancer cells. The study explores how shifts in this ...