Ion channels play a crucial role in many cellular processes, including neuronal communication, muscle contraction or cell proliferation. Most multi subunit ion channels exist in two functional states, ...

In biological systems, complex neuronal networks with highly polarized synaptic gating interfaces are responsible for processing and transmitting intricate biosignals. Inspired by neuronal interfacial ...

S5 mutations disrupt RyR1 channel function, influencing both channel activity and gating mechanisms. This impacts the release of calcium and affects muscle contractions, leading to severe muscle ...