Glomeruli are at the heart of renal function, and yet are only part of an intact nephron. They are of irreplaceable value in maintaining homeostasis. The intact nephron theory: Each nephron is a ...

In the lab, it’s easier to grow simple balls of cells than complex asymmetrical structures with two distinct ends—like the one million filtering units, or nephrons, that make up a human kidney. But ...

The kidneys play a dominant role in regulating both the volume and composition of the extracellular fluid. They function to ensure that the body maintains a homeostatic internal environment. They ...