The 2022 American Academy of Pediatrics guidelines slightly raised phototherapy thresholds for most infants to balance preventing encephalopathy with avoiding the harms of over treatment: This update ...

The present study was undertaken in this institution, therefore, to determine the risks of exchange transfusion and of different levels of bilirubinemia in newborn infants. St. Margaret's Hospital is ...

A systematic review and meta-analysis found no clear advantage for automated red cell exchange. For patients with sickle cell disease (SCD), exchange transfusion has benefits over simple transfusion ...

ACUTE massive hepatic necrosis usually runs a short clinical course. 1 The disease may terminate in death before the liver cells have an opportunity to regenerate and resume function. If the patient ...

Please provide your email address to receive an email when new articles are posted on . Practice patterns vary widely for management of hemolytic disease of the fetus and newborn (HDFN). Researchers ...

Sickle cell disease (SCD) is the most common inherited blood disorder in the U.S. It mainly affects African Americans (1 in 500) and Hispanic Americans (1 in 36,000). People with SCD are born with a ...

There is a lack of evidence-based guidelines for neonatal transfusion practices as seen by the diverse RBC transfusion practices among individuals and institutions. [3,5,27,28,29,30,31,32] The US ...

The clinical presentation is a spectrum of symptoms, including fever and chills, which are the most common symptoms in both AHTR and DHTR. [7] Hypotension, tachycardia, nausea and vomiting are more ...

The Spectra Optia Apheresis System (Terumo BCT) is an apheresis and cell collection platform which can be used in the treatment of sickle cell disease. The purpose of this evaluation is to assess the ...