Gene expression is linked to RNA transcription, which cannot happen without RNA polymerase. However, this is where the similarities between prokaryote and eukaryote expression end. Central to the ...

Nucleosomes are barriers to RNA Polymerase II (Pol II) transcribing along gene bodies in eukaryotes. We found that a fragile “tailless nucleosome” could be generated to resolve the Pol II pausing ...

Proteins are essential biological molecules that perform a vast array of functions crucial for life, from catalyzing ...

Another potentially game-changing discovery has come out of the lab of Feng Zhang, PhD. This time, they uncovered the first programmable RNA-guided system in eukaryotes. Just a few months ago, the ...