Cells have sophisticated methods of sensing stimuli and communicating with nearby cells in response to these stimuli. For example, macrophages can sense environmental stimuli—tissue damage, foreign ...

Autoimmune diseases stem from a complicated interplay of immune dysregulation, characterized by chronic inflammation and the loss of self-tolerance. Cytokines are central to these processes. These ...

Researchers provide essential insights on the molecular activation of the MAP kinase p38?, the final switch triggering the inflammatory response. Inflammation is a cellular coping mechanism when ...

Cytokines and their kin, alternatively called interleukins, growth factors, interferons, necrosis factors, and others, are soluble messengers responsible for communication between nearby cells, ...

People often get immunotherapy as a treatment for cancer. These immunotherapy treatments can be effective, but they may cause your immune system to have an unnatural response. Your body, as a result ...

Cleveland Clinic's Lerner Research Institute was awarded a five-year $12 million grant by the National Cancer Institute, part of the National Institutes of Health, to define how cytokines - proteins ...

October 28, 2022, CLEVELAND: Cleveland Clinic’s Lerner Research Institute was awarded a five-year $12 million grant by the National Cancer Institute, part of the National Institutes of Health, to ...

Last year, around the Thanksgiving holiday, the Omicron SARS-CoV-2 variant emerged, harboring “many more mutations in the spike protein and seemed to be more infectious,” Dr. Taran Gujral, part of the ...

Cytokines are small proteins that serve as the fundamental chemical messengers of the immune system. They also play a key cell signaling role in stem cell biology, relaying messages that direct stem ...