For decades, cancer immunotherapy has focused primarily on CD8+ cytotoxic T lymphocytes as the main executors of tumor cell ...

Tumor biology is increasingly recognized as a field shaped by the intricate interplay between malignant cells and their surrounding microenvironment. Recent ...

The tumor microenvironment (TME) consists of mediators surrounding a tumor, including diverse cell types, blood vessels, and other cellular components. Certain elements of the TME can benefit patients ...

Immunotherapy has revolutionized cancer treatment, yet response rates remain highly variable across tumor types and individual patients. Increasing evidence ...

Intratumoral microbiota—the microbial populations residing within solid tumors—have emerged as pivotal components of the tumor microenvironment (TME), influencing tumor initiation, progression, and ...

Colorectal cancer remains one of the leading causes of cancer-related mortality worldwide, largely due to metastasis and ...

In this piece, I highlight one particular talk that caught my interest — given by Elana Fertig, Dean E. Albert Reece Endowed ...

New research shows how cancer cells use a vitamin B7-dependent pathway to survive in the absence of glutamine, revealing potential drug targets.

A research team has conducted a study exploring the role of the mannose pathway in regulating cell fate decisions in low glucose environments. Their work may hold potential for novel therapeutic ...

Oregon Health & Science University researchers have found that certain nerves that play an integral role in the body's "fight or flight" stress response can support pancreatic tumor growth. These ...