Faulty lipid regulation in CLL patients impairs T-cell function, affecting treatment outcomes and resistance to current therapies. Differences in lipid metabolism between CLL patients and healthy ...

This mind-blowing study revealed how berberine lowers LDL cholesterol through a mechanism that’s completely different from ...

Since then, many scientists, including Lu, who now leads his own research group at Western University, have shown that PIN1 is overexpressed in different types of cancer and regulates many oncogenes ...

In a recent review published in the journal Experimental & Molecular Medicine, researchers reviewed available literature on the role and mechanisms (molecular and pathological) by which cholesterol ...

(A) The classic bile acid synthesis pathway: cholesterol 7α-hydroxylase (CYP7A1) converts cholesterol to 7α-hydroxycholesterol (7α-HOC). The sterol 12α-hydroxylase (CYP8B1) converts the intermediate ...

This article summarizes metabolic reprogramming in prostate cancer (PCa). Early PCa relies more on glycolysis.

This article was reviewed by Felix Gussone, MD. Key Takeaways: Cholesterol is a key building block for testosterone. Through ...