Scientists have uncovered a new way embryonic cells divide when conventional mechanisms fail. Cell division underpins all ...

In order to reprogram readily available cells into specific immune cells that fight various diseases, one must know the ...

New research from Dana-Farber Cancer Institute shows that a new class of drug results in cell death in cancers, such as small cell lung cancer, with a disabled quality control cell cycle checkpoint ...

Inflammation hasto fight pathogens fast—but it can't get out of control. Researchers at the German Cancer Research Center (DKFZ) have now deciphered in more detail how the organism masters this ...

In a major advance for molecular biology and cancer research, scientists have uncovered the molecular mechanisms that control a key step during the activation of cyclin-dependent kinases (CDKs) – the ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 18 (May 3, 2022), pp. 1-12 (12 pages) B and T lymphocytes of the adaptive immune system undergo ...

Scientists at École Polytechnique Fédérale Lausanne (EPFL), and at UNIL-CHUV, University Hospital Lausanne (CHUV) and University of Lausanne (UNIL) have developed a computational method to create ...

Cells degrade components that are no longer needed through autophagy. New results show that a weak molecular interaction is essential for this process. By modifying this interaction, it is possible to ...

GMCL1-dependent degradation of 53BP1 suppresses mitotic surveillance, tuning p53 activation thresholds that govern cell fate decisions and cellular responses after mitosis.

Cell division is an essential process for all life on Earth, yet the exact mechanisms by which cells divide during early ...