Conventional studies on stem cell fates are primarily focused on transcription factors, with the limited consideration for 3D genome architecture. The cohesin complex dynamically restructures ...

When killer T cells of our immune system divide, they normally undergo asymmetric cell division (ACD): Each daughter cell inherits different cellular components, which drive the cells toward divergent ...

The development of humans and other animals unfolds gradually over time, with cells taking on specific roles and functions ...

A new study published in Nature Biotechnology shows that stem cell differentiation is linked to cellular structures called P-bodies, providing a potential means of controlling cell identity.

A cell can act in astonishingly complex ways. It must decide for itself whether to grow and multiply, rest, specialise, age or die. This applies just as much to mammalian cells as it does to seemingly ...

Mitochondria play a crucial role in acquiring pluripotency and determining cell fate. The mitochondrial unfolded protein response (UPR mt) serves as an important retrograde regulatory pathway that ...

Human cells decode dynamics Wnt signals using an anti-resonant filter that suppresses intermediate-frequency inputs and is ...

Shedding light on what determines how cells become what they are meant to be—nerves, bone, muscles, etc.—can also help researchers understand how diseases develop when these biological programs break ...