The discovery of a family with sequence similarity 102 member A (Fam102a) protein as a novel bone remodeling factor that regulates both osteoclast and osteoblast differentiation can aid the ...

Constant remodelling of bones — up to 10% of the total mass every year — helps to maintain the optimal levels of calcium in the blood and also the structural function of the skeleton, but the identity ...

Orthodontic tooth movement is fundamentally driven by the application of controlled mechanical forces to reposition teeth within the alveolar process. This movement is intrinsically linked to alveolar ...

An international collaboration study reveals how evolution and locomotion patterns, such as bipedalism, shaped bone structures through proteins present in the bone matrix. The findings of the study, ...

Birmingham researchers have shown PEPITEM, a naturally occurring peptide (small protein) holds promise as a new therapeutic for osteoporosis and other disorders that feature bone loss, with distinct ...

Sustained hypoxia affects orthodontic tooth movement (OTM) by altering osteoclast and osteoblast differentiation, report researchers from Institute of Science Tokyo, Japan. Hypoxic conditions resulted ...

It’s common to think of your bones as solid and unchanging, but they’re composed of living tissue constantly in flux. Consider: Every year, 15% of your spine and 5% of your hips are replaced with new ...

Bones are the living tissue on which the human skeleton is constructed and play a key role in enabling physical movements. The structural integrity of bones has been attributed to bone remodeling-aa ...

The narrative around bone health has long been dominated by a singular focus: calcium consumption. Yet despite widespread calcium supplementation, osteoporotic fractures affect approximately one in ...

Fam102a-Rbpjl axis in osteoblast differentiation reveals significant insights into bone remodeling and may aid the development of therapeutic strategies. Bones are the living tissue on which the human ...