The lower hinge of immunoglobulin G (IgG), an overlooked part of the antibody, acts as a structural and functional control ...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomic surveillance has revealed thousands of alterations in structural and non-structural proteins. However, by the end of 2020, viral ...
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New platform improves prediction of human antibody drug responses
An international research consortium, led by scientists at VIB and UGent, has developed a new platform that could change how antibody medicines are tested and brought to patients. The work, published ...
BOSTON & CAMBRIDGE, England--(BUSINESS WIRE)--Alchemab Therapeutics, a biotechnology company focused on the discovery and development of naturally-occurring protective antibodies and immune repertoire ...
Antibodies, also known as immunoglobulins, are specialized proteins produced by the immune system to identify and neutralize foreign invaders, such as viruses, bacteria, and other pathogens. They are ...
Post-translational modifications contribute to the structure, function, and efficacy of the therapeutic antibody. The extent to which the antibody is modified and the location of the modifications all ...
BOSTON & CAMBRIDGE, England--(BUSINESS WIRE)--Alchemab Therapeutics, a biotechnology company focused on the discovery and development of naturally-occurring protective antibodies and immune repertoire ...
b) an Fc domain comprising amino acid substitutions M428L/N434S as compared to a human Fc polypeptide, wherein numbering is according to the EU index of Kabat, wherein said anti-C5 antibody with said ...
Researchers have discovered a new function of anti-HIV-1 antibodies by applying cutting-edge microscopy techniques to in vitro viral cultures. The scientists found that certain antibodies already ...
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