Ciclosporin A (CyA) was the cornerstone of rescue medical therapy for steroid-refractory acute severe colitis until the advent of anti-TNF agents. CyA is a competitive calcinuerin inhibitor with ...

Please provide your email address to receive an email when new articles are posted on . “Several early predictors of IVS failure have been suggested, including clinical parameters such as the number ...

Acute cholangitis, also known as ascending cholangitis, is a serious disorder of the biliary system, which can be life-threatening, if left untreated. The most frequent reason of obstruction of the ...

Things haven’t exactly gone swimmingly for the USA Swimming team at the World Aquatics Championships in Singapore. Several members have received a figurative and literal blow to the gut from what’s ...

Acute severe ulcerative colitis (ASUC) is associated with a significant risk of colectomy and requires timely and effective medical intervention to reduce morbidity and mortality. However, designing ...

Ulcerative colitis (UC) is a chronic inflammatory disease of the colon driven by an abnormal immune response. It typically begins in the rectum and spreads continuously, occasionally involving a cecal ...

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

Ulcerative colitis is a chronic relapsing and remitting inflammatory disorder that can generally be managed successfully with maintenance oral medications. However, approximately 15% of patients with ...