Crinetics Initiates Phase 2/3 Pediatric Trial Evaluating Atumelnant in Congenital Adrenal Hyperplasia (CAH)

The study will be conducted in three phases. Part A is a Phase 2, open-label, semi-sequential dose-ranging portion of the study. Part B is the Phase 3, double-blind, randomized, placebo controlled ...
Yahoo Finance

Crinetics Pharmaceuticals Lead ACTH Antagonist for Congenital Adrenal Hyperplasia and Cushing’s Disease (CRN04894) Advances into Phase 1 Study

SAN DIEGO, Feb. 04, 2021 (GLOBE NEWSWIRE) -- Crinetics Pharmaceuticals, Inc. (Nasdaq: CRNX), a clinical stage pharmaceutical company focused on the discovery, development, and commercialization of ...
Nature

ACTH and cortisol cord plasma concentrations in preterm and term infants

To measure the adrenocorticotropic hormone (ACTH) and cortisol (F) cord plasma levels in preterm and term infants in relation to their mode of delivery. We studied 180 newborns appropriate for ...
Healthline

ACTH (Cosyntropin) Stimulation Test

Your pituitary gland is a pea-sized gland located at the base of your brain. It produces many types of hormones, including the adrenocorticotropic hormone (ACTH). ACTH stimulates the adrenal glands, ...
Medindia

Medications and their Potential to Cause Increase 'Ectopic ACTH syndrome'

This page lists all known medications that could potentially lead to 'Ectopic ACTH syndrome' as a side effect. It's important to note that mild side effects are quite common with medications. The ...
Yahoo Finance

Crinetics Pharmaceuticals’ Oral ACTH Antagonist, CRN04894, Demonstrates Pharmacologic Proof-of-Concept with Dose-Dependent Cortisol Suppression in Single Ascending Dose ...

SAN DIEGO, Aug. 10, 2021 (GLOBE NEWSWIRE) -- Crinetics Pharmaceuticals, Inc. (Nasdaq: CRNX), a clinical stage pharmaceutical company focused on the discovery, development, and commercialization of ...
The New England Journal of Medicine

ACTH-Producing Tumor of the Pituitary Gland

THE association of adrenal hyperplasia with basophil tumors of the pituitary gland was first suggested by Cushing. 1 This type of tumor has since been thought to be at least one cause of Cushing's ...
Business Wire

BioSim Pharmaceuticals Selects CPC Scientific as Key Supplier in the Manufacture of BioSim’s ACTH Gel

SEATTLE--(BUSINESS WIRE)--BioSim Pharmaceuticals, Inc. today announced that it has selected CPC Scientific to supply BioSim with their cGMP ACTH peptide. BioSim’s ACTH Gelatin Depot 80 IU/mL product ...
The New England Journal of Medicine

Effect of ACTH on Induced Fever

ONE of the most striking effects of the administration of pituitary adrenocorticotrophic hormone (ACTH) to patients with febrile illnesses is the prompt defervescence that is frequently observed. The ...
Renal & Urology News

Adrenocorticotropic Hormone May Be an Alternative Therapeutic Option for Acute Gout

Researchers evaluated the adrenocorticotropic hormone as an alternative therapeutic option for acute gout, and its potential mechanisms of action. Adrenocorticotropic hormone (ACTH) may be a ...

Crinetics Pharmaceuticals, Inc.: Crinetics Initiates Phase 2/3 Pediatric Trial Evaluating Atumelnant in Congenital Adrenal Hyperplasia (CAH)

First in class study of an investigational ACTH receptor antagonist aims to address significant unmet need in children and adolescents with classic CAHSAN DIEGO, Jan. 22, 2026(Nasdaq: CRNX) today anno ...